Magnesium Citrate

Magnesium citrate is a versatile compound with multiple medical and dietary applications. It serves as an effective saline laxative, providing relief from constipation by softening stool and promoting bowel movements. Additionally, it is used to thoroughly empty the bowel before major surgeries or colonoscopies, ensuring clear visibility during medical procedures. As a dietary supplement, magnesium citrate offers a bioavailable source of magnesium, supporting vital bodily functions like muscle and nerve activity. Beyond these uses, magnesium ions in magnesium citrate may also play a role in regulating gut activity, stimulating nitric oxide synthesis, and influencing the biosynthesis of platelet activating factor.


Application of Dipotassium Hydrogen Phosphate

Magnesium citrate is used medicinally as a saline laxative and to completely empty the bowel prior to a major surgery or colonoscopy. It is available without a prescription, both as a generic and under various brand names. It contains 11.23% magnesium by weight.

Mechanism of Action

  • It exerts its laxative effect primarily through its osmotic properties.
  • This increased water content softens stool and stimulates bowel movements, aiding in the relief of constipation.
  • When used as a dietary supplement, magnesium citrate provides a bioavailable source of magnesium ions (Mg2+).
  • Benefits of Magnesium Citrate

  • It is an effective and commonly used saline laxative for the relief of constipation.
  • This ensures a clear and unobstructed view of the colon during medical procedures, facilitating accurate diagnosis and treatment.
  • Magnesium ions may play a role in regulating gut activity by stimulating NO synthase and PAF biosynthesis.
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